ISSN 1662-4009 (online)

ey0017.9-17 | Cancer Treatment, Growth and Growth Hormone | ESPEYB17

9.17. Final height in growth hormone-deficient childhood cancer survivors after growth hormone therapy

G Rodari , A Cattoni , A Albanese

To read the full abstract: J Endocrinol Invest. 2020 Feb;43(2):209–217. giulia.rodari@unimi.itGrowth hormone deficiency (GHD) is the most common endocrine late effect in children with tumours involving the hypothalamus-pituitary (HP) area or exposed to cranial, craniospinal or total body radiotherapy (RT). The location of brain tumours in continuity with the sellar/suprasellar area and HP radiatio...

ey0016.9-13 | Cancer Treatment and Growth Disorders | ESPEYB16

9.13. The predictive value of insulin-like growth factor 1 in irradiation-dependent growth hormone deficiency in childhood cancer survivors

A Cattoni , E Clarke , A Albanese

To read the full abstract: Horm Res Paediatr. 2018; 90(5): 314This single-centre, retrospective study analyzes the screening role of low IGF-1 levels in the diagnosis of growth hormone deficiency (GHD) in a cohort of 158 childhood cancer survivors (CCS) and in a selected sub-cohort of 117 CCS who received radiation for tumours not directly involving the hypothalamic-pituitary (HP) area (...

ey0018.9-7 | Surveillance strategies of endocrine complications | ESPEYB18

9.7. Hormonal replacement therapy in adolescents and young women with chemo- or radio-induced premature ovarian insufficiency: Practical recommendations.

A Cattoni , F Parissone , I Porcari , S Molinari , N Masera , M Franchi , S Cesaro , R Gaudino , P Passoni , A. alessandro.cattoni@unimib.it Balduzzi

Blood Rev. 2021; 45: 100730. https://pubmed.ncbi.nlm.nih.gov/32654893/This practical treatment protocol was developed by an experienced multidisciplinary team following a critical and updated systematic review of the literature.Hypogonadism is a common finding after antineoplastic treatment. It can either result from a primary gonadal disorder (due to pelvic irradiati...

ey0019.9-13 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.13. Serum anti-Mullerian hormone as a marker of ovarian reserve after cancer treatment and/or hematopoietic stem cell transplantation in childhood: proposal for a systematic approach to gonadal assessment

S Molinari , F Parissone , V Evasi , Lorenzo P De , MG Valsecchi , S Cesaro , D Fraschini , R Sangalli , G Cacace , A Biondi , A Balduzzi , A Cattoni

s.molinari3@campus.unimib.it Eur J Endocrinol. 2021; 185: 717-728. PMID: 34519276.Brief Summary: This retrospective study, involving two Italian centers, enrolled post-pubertal female patients who had been treated with gonadotoxic therapies for hematological malignancies and/or hematopoietic stem cell transplantation (HSCT) before the age of 18 years. Several studies have r...

ey0020.7-2 | Gonadal Function and Fertility Issues in Childhood Cancer Survivors | ESPEYB20

7.2. Towards an individualized management of pubertal induction in girls with hypogonadism: insight into the best replacement outcomes from a large multicentre registry

G Rodari , S Federici , T Todisco , G Ubertini , A Cattoni , M Pagano , F Giacchetti , E Profka , V Citterio , D Messetti , V Collini , D Soranna , E Carbone , M Arosio , G Mantovani , L Persani , M Cappa , M Bonomi , C Giavoli

Brief summary: This longitudinal observational multicentre retrospective study, collected data on 95 young prepubertal or early pubertal girls (age >10.9 years, Tanner stage ≤2) with premature ovarian failure (POI) or hypogonadotropic hypogonadism (HH). Their hypogonadism was due to different causes and was treated with transdermal 17β-oestradiol, with a follow-up of at least 1 year. The study aimed to identify the most physiological and effective therapeutic sc...